Dr. Katie Bentley

Postdoctoral Fellow

Vascular Biology Laboratory,
Cancer Research UK London Research Institute,
Lincoln's Inn Fields, London WC2a 3PX, UK
email: Katie.Bentley at cancer.org.uk


List of publications (click on title to download drafts)


Papers:

Guarani, V., Deflorian, Claudio A. Franco, Marcus Krüger, Li-Kun Phng, Katie Bentley, Louise Toussaint, Franck Dequied, Raul Mostoslavsky, Mirko H.H. Schmidt, Barbara Zimmermann, Ralf P. Brandes, Marina Mione, Christoph H. Westphal, Thomas Braun, Andreas M. Zeiher, Holger Gerhardt, Stefanie Dimmeler, Michael Potente, (2011) Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase. Nature. In Press.

Bentley, K., Clack C., Cox, E. J. (2011) Diatom colony formation: A computational study predicts a single mechanism can produce both linkage and separation valves due to an environmental switch.Journal of Phycology. In Press

Black, E. and Bentley, K. (2011) An empirical study of a deliberation dialogue system. Lecture Notes in Computer Science (TAFA workshop, IJCAI conference, Barcelona) In Press

Jakobsson, L., Franco, C., Bentley, K., Collins, R., Ponsioen, B., Aspalter, I. M., Rosewell, I., Busse, M., Medvinsky, A., Schulte-Merker, S., Gerhardt, H. (2010) Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting. Nature Cell Biology. doi:10.1038/ncb2103

Bentley, K., Mariggi, G., Gerhardt, H. and Bates, P. A. (2009) Tipping the balance: Robustness of Tip Cell Selection, Migration and Fusion in Angiogenesis. PLoS Computational Biology 5(10): e1000549. doi:10.1371/journal.pcbi.1000549 .

Jakobsson, L., Bentley, K., Gerhardt,H. (2009) VEGFRs and Notch: a dynamic collaboration in vascular patterning. J. Biochem. Soc. Trans. 37(6).

Bentley, K., Gerhardt, H. and Bates, P. A. (2008). Agent-based simulation of notch mediated tip cell selection in angiogenic sprout initialisation. Journal of Theoretical Biology, 250(1):25-36.

Bentley, K., Cox, E. J., Bentley, P. J. (2005). Nature's Batik: A Computer Evolution Model of Diatom Valve Morphogenesis.   Journal of Nanoscience and Nanotechnology 5(1): 25-34. (or email me nicely for a draft).

Bentley, K and Clack, C. (2005). Morphological Plasticity: Environmentally Driven Morphogenesis. In Advances in Artificial Life (Lecture notes in AI series) Proceedings of the Eighth European Conference on Artificial Life (ECAL '05). Capcarrere, M. et al. (eds). Pp. 118-127. Springer-Verlag.

Bentley, K and Clack, C. (2004). The Artificial Cytoskeleton for Lifetime Adaptation in Morphology. In Workshop Proceedings of the 9th International Conference on the Simulation and Synthesis of Living Systems (Alife IX). Bedau, M., Husbands, P., Hutton, T., Kumar, S., Suzuki, H.(Eds.)  Pp 13-16.

Bentley, K. (2002). Exploring Aesthetic Pattern Formation. In Proceedings of 5th Annual International Conference on Generative Art, Milan. Chapter 20.1.


PhD Thesis:

Bentley, K. (2006) Dept. Computer Science, UCL. Adaptive Behaviour Through Morphological Plasticity in Natural and Artificial Systems (pdf) or zipped version


Poster Presentations:

Bentley, K., Jakobsson, L., Mariggi, G., Bates. P. A, and Gerhardt, H. (2008) Tipped for the top: computer simulations of Notch signaling during sprouting reveal the tip cell phenotype to be continually in flux as cells fight for the tip position. (POSTER) NAVBO Developmental Vascular Biology Workshop IV, Monterey Bay California, February 2010 [WINNER Outstanding Poster Prize] abstract.

Bentley, K., Sauvaget, D. and Gerhardt, H. (2008) Dll4/Notch oscillations disrupt vascular patterning during tumour angiogenesis . (POSTER) 12th International Symposium on Anti-Angiogenic Agents. San Diego, February 2010 link

Bentley, K. Gerhardt, H. and Bates, P. A. (2008) COMPUTATIONAL MODELLING OF CELL MIGRATION IN ANGIOGENESIS. (POSTER) Frontiers in Cell Migration, NIH, Bethesda, Sept 2008. Abstract (page 102) Poster

Bentley, K. Gerhardt, H. and Bates, P. A. (2007) Computer Simulation of notch mediated tip cell selection in angiogenesis. (POSTER) NCRI conference, Birmingham, Sept 2007

Bentley, K. (2003) Evolving Complex Forms to Self-Assemble a Self-Replicating Functional Form. (POSTER) In Evolvability, Genetics & Development in Natural and Constructed Systems: Abstracts of the EPSRC Evolvability Network Symposium. Dept. Comp. Sci., University of Hertfordshire, Technical Report No: 389. C. L. Nehaniv, P. J. Bentley, S. Kumar (Eds.) Pp 17. Abstract, Poster(10 MB).


Slide Presentations:

Tipping the Balance: agent-based modelling of tip cell selection, migration and fusion sprouting

- Invited speaker UCLA, Los Angeles 2010

- Invited speaker Angionet meeting Dundee 2009

- invited seminar Centre for Mathematical Biology. Oxford University, June 2008

Agent-based simulation of notch mediated tip cell selection during angiogenic sprouting

- invited seminar Computer Science Dept. Imperial College London, March 2008

- invited seminar Computer Science Dept. Kings College London, Dec 2007

- invited seminar Computer Science Dept. University of Sheffield, Nov 2007

- invited seminar Mathematics Dept. University of Nottingham, Nov 2007

- invited seminar, 3rd Angionet Meeting Colraine, Northern Ireland 18-20th June 2007

Morphological Plasticity: Environmentally Driven Morphogenesis. Eighth European Conference on Artificial Life (ECAL '05). September 5-9th 2005, Kent, Canterbury. 

Morphological plasticity: Dynamic, Situated Morphologies. Workshop on the Dynamical Systems approach to Life and Cognition organised by activate.d (active agents and their environments as dynamical systems reading group), University of Sussex, 8-9th March 2005.

Morphological plasticity as Adaptive Behaviour in Natural and Artificial Systems. Bloomsbury Centre for Bioinformatics seminar, Birkbeck College, February 16th 2005.

The Artificial cytoskeleton for Lifetime Adaptation of Morphology. Ninth International Conference of Artificial Life, Boston, September 2004

(Developing the Artificial Cytoskeleton: adaptation through morphogenesis in diatoms.  Nature Inspired Computing Consortium meeting 10/11 Feb, London 2004.

Exploring Aesthetic Pattern Formation.  nUCLEAR talk, CS, UCL 2002 and Generative Art Conference Presentation, Milan 2002


In the Media:

Cohen, P. NATURAL GLASS.  NewScientist.  Cover date 17 January 2004. p 26

''Making intricate nano-components that cost next to nothing is easy if you have the right workforce. Call in the algae''  Article about the papers in JNN special issue on diatom nanotechnology (Bentley, K, et al. JNN. 2005).

 

 


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